SARTORIUS – Resolute® Flowdrive SU
Resolute®Flowdrive SU Single-use chromatography systems in combination with resolute columns and membrane adsorbers provide unparalleled flexibility for multi-product manufacturing at pilot/clinical scale.
In addition, our chromatography portfolio includes mixed-mode resins and membrane adsorbers that enable stepwise intensification to meet industry needs for higher process efficiency. Sartorius enables you to conveniently scale from process development scale to clinical processing with industry-accepted single-use chromatography technologies (both hardware and consumables).
Our global Integrated Solutions team (INSO) will review your specific process needs before proposing a solution that exactly meets all the process requirements. This solution could include our standard platform design for the Sartorius single-use chromatography system, along with standard totes and mixers, or it might lead to the creation of a custom design.
Available Models
Single-Use Batch Chromatography System
| System Capacity | 3/8 in. Flow kits | ½ in. Flow kits |
|---|---|---|
| Volumetric Flow | 18 to 600 L/hr | 36 to 900 L/hr |
| Tubing ID | 3/8 in. (0.95cm) | ½ in.(1.27cm) |
| Holding-up Volume | 0.5 L | 1.0 L |
| Column Diameter | 10-60cm | 10-60cm |
| Pressure Rating | 0 to 4 bar | 0 to 4 bar |
| System Pumps | Up to ×2 diaphragm (single-use) | Up to ×2 diaphragm (single-use) |
| Inlet | 6 per pump | 6 per pump |
| Outlets | 4 | 4 |
For customers who are performing clinical or commercial manufacture, the Resolute®️ Flowdrive SU system delivers precision isocratic and gradient chromatography in a user optimized architecture that equals the performance and functionality of equivalent stainless-steel systems.
- Available in Isocratic (1-pump) and gradient (2-pump) variants, covering wide flow range for 200-2000L batches
- Typically sufficient for columns from 10 to 60 cm diameter and membranes from 0.075 to 3 L
- Unique pinch block valve highly reduces the flow kit change-over time (typically 10-30 min)
- Integrated in-line buffer dilution reduces the need to make and transport buffers
- Pressure rating up to 4 barg
- Intuitive Process Step Editor control software, same platform for single-use TFF
- “cGMP” compliant design and documentation
Key Features
- Isocratic and gradient configurations for resin, monolith, and membrane chromatography
- Flexibility in using 3/8 in. and 1/2 in. single-use flow kits
- Unique pinch valve block technology simultaneously reduces the void volume and enables easy flow kit installation
- Ready to operate with pre-calibrated single-use sensors
- Compact system design with maneuverable HMI
- cGMP compliant design and documentation
Key Industries
- Biopharmaceutical and Biotechnology
Brand
The Sartorius Group is a leading international partner of the biopharmaceutical industry and the research sector. We are helping biotech scientists and engineers across the entire globe to develop and manufacture medications from the first idea to production. So more people will have access to better medicine.